The research projects are categorised according to the six priority areas of the national research programme. Each area is described in detail in the programme’s strategic research agenda (in Swedish).
External link.
Prevention
The area provides knowledge about responsible use of antibiotics and how measures for preventing and controlling the spread of disease among humans and animals are developed and evaluated.
More than 8 000 persons are living with HIV in Sweden, and 500 new cases are added every year. These patients (with weak immune defence systems) are at particular risk of developing fungal infections. The purpose of the project is to investigate how the immune defence against HIV in mucous membranes is impacted by simultaneous fungal infections.
Project leader: José Pedro Lopes
Period: 2021-2024
Higher education institution: Karolinska institutet
Grant form: Grants for employment or scholarships
Categorised by area: Prevention
Many infections in conjunction with medical implants are complicated by the ability of bacteria to develop what is known as ‘biofilm’. To cure this type of infections, both large-scale surgery and long subsequent antibiotic therapy are needed. The project aims to investigate whether the therapy outcome can be improved by using analyses of antibiotic resistance in biofilm to choose the correct antibiotic therapy.
Project leader: Jonatan Tillander
Period: 2021-2023
Organisation: Västra Götaland Region
Grant form: Grant for research time
Categorised by area: Prevention
Before the era of antibiotics, complications arising from ear inflammation was one of the most common causes of death among children. The increasing problem of antibiotic resistance means that antibiotics are no longer used as the standard therapy for ear inflammation. The purpose of the network is to investigate what causes certain ear inflammations to develop complications, so that we in future can tailor the therapy for acute ear inflammation.
Project leader: Marie Gisselsson-Solén
Period: 2021-2022
Higher education institution: Lund University
Grant form: Grant for research time
Categorised by area: Prevention
By studying the metabolism of patients with suspected infection, the researchers behind the project hope to improve the chances of rapid diagnosis and treatment of sepsis (blood poisoning).
Project leader: Alicia Edin
Period: 2020–2021
Higher education institution: Umeå University
Grant form: Grant for research time
Categorised by area: Prevention
Through studies of the immune system, the project leader wants to improve the methods for diagnosis and treatment of sepsis (blood poisoning).
Project leader: Fredrik Kahn
Period: 2020–2021
Organisation: Region Skåne
Grant form: Grant for research time
Categorised by area: Prevention, Medicines and vaccines
Tolerance of antibiotics means that it takes longer than usual to kill a bacterium during antibiotic treatment. Persistence against antibiotics means that a small number of bacteria survive the antibiotic treatment, despite not being resistant. The purpose of the project is to develop a method for measuring bacteria’s tolerance of and persistence against antibiotics during an infection. This could lead to better treatment and reduced risk of antibiotic resistance developing.
Project leader: Fredrik Resman
Period: 2020-2021
Organisation: Region Skåne
Grant form: Grant for research time
Categorised by area: Prevention, Medicines and vaccines
The aim is to develop a sequence-based method for describing a bacterium’s ability to cause disease, and thereby a risk of causing blood poisoning.
Project leader: Susanne Sütterlin
Period: 2020–2021
Higher education institution: Uppsala University
Grant form: Grant for research time
Categorised by area: Prevention
The aim of the project is to contribute new knowledge and ways of working that lead to optimal treatment with antibiotics to achieve complete clinical healing and at the same time reduce the risk of side effects and the emergence of resistant bacteria.
Project leader: Thomas Tängdén
Period: 2020–2021
Higher education institution: Uppsala University
Grant form: Grant for research time
Categorised by area: Prevention, Medicines and vaccines
The project aims to prevent recurrent urinary tract infections and blood poisoning caused by antibiotic-resistant E. coli bacteria.
Project leader: Åse Balkhed Östholm
Period: 2019–2020
Higher education institution:Uppsala University
Grant form: Grant for research time
Categorised by area: Prevention
The aim of the project is to map and analyse the bacteria and virus that are involved in serious deterioration episodes of COPD in Sweden.
Project leader: Helena Nyström
Period: 2019–2020
Higher education institution: Umeå University
Grant form: Grant for research time
Categorised by area: Prevention, Monitoring
The aim of the project is to develop better indicators for when preventive antibiotic therapy should be given before gall bladder surgery.
Project leader: Gonas Jaafar
Period: 2019–2020
Higher education institution: Karolinska Institutet
Grant form: Grant for research time
Categorised by area: Prevention
Monitoring
The area provides knowledge that enables the development and evaluation of monitoring of resistance and care-related infections.
Antibiotic resistance makes infections difficult or impossible to heal, which leads to great suffering and high healthcare costs. It is therefore important to slow down the development of resistant bacteria. Monitoring of antibiotics therapy and the occurrence of resistant bacteria is an important part of this work. The purpose of the project is to analyse antibiotics use and antibiotic resistance in Swedish eye healthcare.
Project leader: Tomas Bro
Period: 2021–2023
Organisation: Region Jönköpings län
Grant form: Grant for research time
Categorised by area: Övervakning
Diagnostics
The area uses research initiatives to develop and introduce better diagnostics of resistant infections in humans and animals.
Today, it can take up to five days from taking a sample to knowing whether a bacterium is resistant to antibiotics. The project is about developing a method for quicker determination of bacterial resistance.
Project leader: Sofia Somajo
Period: 2019–2020
Higher education institution: Region Kronoberg
Grant form: Grant for research time
Categorised by area: Diagnostics
Medicines and vaccines
The area uses research initiatives to increase the current therapy alternatives for humans and animals by developing new antibiotics or alternatives to antibiotics, and by improving existing antibiotics.
Bacteria use many different mechanisms to increase their ability to survive and contribute to resistance to medicines. The aim of the network is to promote research collaboration and information-sharing between different actors in order to stimulate the development of new, sustainable diagnostic and therapeutic strategies.
Project leader: Irfan Ahmad
Period: 2021-2022
Higher education institution: Umeå University
Grant form: Network grant
Categorised by area: Medicines and vaccines, Diagnostics
The need to replace hip prostheses is increasing, and one of the most feared complications in orthopaedic surgery is prosthesis infection. The applicant wants to use a clinical study to investigate whether an antibiotic-impregnated implant can reduce the number of prosthetic infections following surgery.
Project leader: Jörg Schilcher
Period: 2021–2023
Higher education institution: Linköping University
Grant form: Grant for research time
Categorised by area: Medicines and vaccines
The purpose of the network is to create a centre for Sweden’s university-linked infection clinics to carry out clinical research into antibiotics therapy and antibiotic resistance. The centre will facilitate clinical studies focusing on interventions, such as changed working practices, diagnostics and treatment.
Project leader: Pontus Naucler
Period: 2021–2022
Higher education institution: Karolinska Institutet
Grant form: Network grant
Categorised by area: Medicines and vaccines
The purpose of the network is to coordinate research questions and knowledge gaps in the use of antibiotics and antimicrobial resistance in primary care. We will be focusing on urinary tract infections and airway infections in primary care, as these are the most common infections.
Project leader: Katarina Hedin
Period: 2021–2022
Organisation: Region Jönköpings län
Grant form: Network grant
Categorised by area: Medicines and vaccines
Cancer patients who are receiving cytotoxin therapy have reduced immune defence and are extra sensitive to infection. The project aims to develop a new method for developing concentrates of neutrophiles (a type of white blood cells) for treating antibiotic-resistant infections.
Project leader: Roland Fiskesund
Period: 2020-2023
Higher education institution: Karolinska Institutet
Grant form: Grant for research time
Categorised by area: Medicines and vaccines
The occurrence of antibiotic-resistant mycobacterial infections, such as tuberculosis, is increasing. The project aims to investigate whether new combinations of existing antibiotics can be used against mycobacterial infections that are otherwise difficult to treat.
Project leader: Lina Davies Forsman
Period: 2020-2021
Organisation: Stockholm County Council
Grant form: Grant for research time
Categorised by area: Medicines and vaccines
The project aims to investigate a strategy for shortening the treatment of patients with tuberculosis by optimising the dosage of the therapy medicines.
Project leader: Katarina Niward
Period: 2020-2021
Higher education institution: Linköping University
Grant form: Grant for research time
Categorised by area: Medicines and vaccines
Most patients treated in an intensive care unit (ICU) will at some stage be treated with antibiotics. The project aims to investigate different aspects of how the use of antibiotics for critically ill patients can be improved.
Project leader: Fredrik Sjövall
Period: 2020-2021
Organisation: Region Skåne
Grant form: Grant for research time
Categorised by area: Medicines and vaccines, Prevention
The project aims to investigate whether other types of antibiotics than Ciprofloxacin can be used in the treatment of urological infections.
Project leader: Johan Styrke
Period: 2020-2021
Higher education institution: Umeå University
Grant form: Grant for research time
Categorised by area: Medicines and vaccines, Prevention
The project leader wishes to investigate whether carriers of certain types of multi-resistant E. coli bacteria (in the gut) are at greater risk of developing infections, and whether bacteriophages can be used as therapy for de-colonising the carrier and reducing the risk of future infections.
Project leader: Malin Vading
Period: 2019–2020
Organisation: Karolinska Institutet
Grant form: Grant for research time
Categorised by area: Medicines and vaccines, Prevention
The aim of the project is to find new points of attack in the development of antibiotics and vaccines against pneumococcal infections.
Project leader: Karin Blomqvist
Period: 2019–2020
Higher education institution: Karolinska Institutet
Grant form: Grant for research time
Categorised by area: Medicines and vaccines
The project aims to develop new therapy methods against infections caused by Gram-negative bacteria, by using specific characteristics of the bacteria’s outer membranes.
Project leader: Magnus Paulsson
Period: 2019–2020
Higher education institution: Lund University
Grant form: Grant for research time
Categorised by area: Medicines and vaccines
Environment
The area aims to provide increased knowledge about the role of the environment in the origin and spread of antibiotic resistance, and the effect that emissions of antibacterial substances and resistant bacteria in the environment have had on the health of humans and animals.
The project aims to increase our knowledge of the importance of the environment in the origin, development and spread of antibiotic resistance.
Project leader: DG Joakim Larsson
Period: 2019–2024
Higher education institution: University of Gothenburg
Grant form: Research environment grant
Categorised by area: Environment
The Government established seven national research programmes in 2016
The programmes run for ten years, and the Swedish Research Council is responsible for two of them: Antimicrobial resistance and Migration and integration.
Formas is responsible for the research programmes Food, Climate, and Sustainable spatial planning. Read about the programmes on Formas’ websiteLänk till annan webbplats. External link.
Forte is responsible for the research programmes Applied welfare research, and Working life research. Read about the programmes on Forte’s website External link.
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