Chemical Biology Consortium Sweden, CBS
The Chemical Biology Consortium Sweden (CBCS) is a distributed infrastructure that provides small molecule libraries, instruments, methods and expertise for identifying and further developing small molecules for studies of biological systems.
Chemical biology is a multidisciplinary field, where the interaction between small molecules and biomolecules are used as tools for identifying, studying and modulating biological processes. The purpose is to understand cellular processes at molecular level, and to influence these.
The greatest need for chemical biology exists within biomedical research, and the field is closely linked to both pharmaceutical development and to health and medical care, but the techniques are also used within several other research disciplines.
The work at the Chemical Biology Consortium Sweden (CBCS) research infrastructure concerns tasks such as designing cellular or molecular systems for investigating a specific biological process, managing and designing ‘small molecule libraries’, large-scale screening to identify active small molecules, and synthesising and modifying small molecules.
CBCS can also help researchers to identify the biological function of small molecules, and develop systems for large-scale testing of small molecules and existing medicines in cells from patient tissue, to support the research field of precision medicine.
The primary nodes of CBCS are located at Karolinska Institutet and Umeå University, and forms part of SciLifeLab. There are also satellite nodes with initial screening facilities at Uppsala University, Linköping University, Lund University and the University of Gothenburg.
Read more on Chemical Biology Consortium Sweden External link.